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SAHM Position & Statement Papers
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- Position paper
Depot Medroxyprogesterone Acetate and Bone Mineral Density in Adolescents—The Black Box Warning: A Position Paper of the Society for Adolescent Medicine
Journal of Adolescent HealthVol. 39Issue 2p296–301Published in issue: August, 2006- Barbara A. Cromer
- Delia Scholes
- Abbey Berenson
- Tim Cundy
- M. Kathleen Clark
- Andrew M. Kaunitz
Cited in Scopus: 121The purpose of this Position Paper is to review the published Black Box Warning regarding depot medroxyprogesterone acetate (DMPA) and bone loss as it relates to adolescent girls. The scientific findings that prompted the Food and Drug Administration to issue the warning are reviewed and the following additional issues are considered: (1) likely low risk of fracture related to DMPA use, (2) evidence of at least partial recovery after discontinuation of the method, and (3) the need to balance the physical, social and economic cost of adolescent pregnancy versus the immediate and long-term impact of DMPA on bone.
