Abstract
Purpose
Adolescent cannabis use is associated with adverse health outcomes. The impact of
cannabis legalization on adolescent cannabis-related hospitalizations remains unknown.
We sought to assess whether state cannabis legalization is associated with adolescent
cannabis-related hospitalizations.
Methods
We conducted a retrospective cohort study of adolescent (11–17 years) hospitalizations
at children’s hospitals between January 1, 2008 and December 31, 2019 using the Inpatient
Essentials database. We investigated differences in adolescent cannabis-related diagnosis
during a hospitalization by state cannabis legalization status, including states with
no legal use to medical cannabis laws (MCLs) and states with MCLs to nonmedical (>21 years
old) cannabis laws (NMCLs).
Results
Of 1,898,432 adolescent hospitalizations in 18 states and Washington, DC, there were
37,562 (2%) hospitalizations with a cannabis-related diagnosis, with 8,457 (23%) in
states with no legal use, 20,444 (54%) in MCL states, and 8,661 (23%) in NMCL states.
There was an increase in adjusted odds of a cannabis-related hospitalization in MCL
(odds ratio 1.05, 95% confidence interval 1.04–1.06) and NMCL states (odds ratio 1.03,
95% confidence interval 1.02–1.03) between 2008 and 2019. Characteristics associated
with the greatest increase in adjusted odds of a cannabis-related hospitalization
postpolicy change included adolescents without an underlying mental health or other
substance use disorder in MCL and NMCL states (p < .001) and younger age in NMCL states (13 vs. 16 and 17 years old, p = .02 and p = .02).
Conclusions
Cannabis-related adolescent hospitalizations at children’s hospitals are increasing,
with a disproportionate increase postlegalization in states with NMCLs. Interventions
are warranted to increase cannabis use identification and treatment among at-risk
adolescents in the hospital-based setting.
Keywords
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References
- The health effects of cannabis and cannabinoids: Current state of Evidence and Recommendations for research.The National Academies Press, Washington, DC2017 (Washington, DC)
- Office of the Surgeon general AS for H (ASH). Surgeon General’s Advisory: Marijuana Use & the developing Brain. HHS.gov.(Available at:) (Published August 29, 2019. Accessed October 1, 2020)
- Results from the 2018 national survey on Drug Use and health (NSDUH): Detailed Tables. Substance abuse and mental health Services administration (SAMHSA), Rockville, MDAugust 20.(Available at:)
- Persistent cannabis users show neuropsychological decline from childhood to midlife.Proc Natl Acad Sci USA. 2012; 109: E2657-E2664
- Meta-analysis of the association between the level of cannabis Use and risk of psychosis.Schizophr Bull. 2016; 42: 1262-1269
- Marijuana use is associated with suicidal Ideation and behavior among US adolescents at rates similar to Tobacco and Alcohol.Arch Suicide Res. 2020; : 1-14
- Trajectories of adolescent Alcohol and cannabis Use into young adulthood.Addiction. 2007; 102: 607-615
- Cannabinoid hyperemesis: Cyclical hyperemesis in association with chronic cannabis abuse.Gut. 2004; 53: 1566-1570
- Cannabinoid hyperemesis Syndrome: Diagnosis, Pathophysiology, and treatment-a Systematic review.J Med Toxicol. 2017; 13: 71-87
- Cannabis policy heterogeneity and effects on research—Complexity Expected.JAMA Netw Open. 2021; 4: e212545
- Marijuana Use and potential Implications of marijuana legalization.Pediatr Rev. 2020; 41: 61-72
- Risk and Protective Factors and Estimates of substance Use initiation: Results from the 2016 national survey on Drug Use and health.in: CBHSQ Data Review. Substance Abuse and Mental Health Services Administration (US). 2012 (Available at:)http://www.ncbi.nlm.nih.gov/books/NBK481723/Date accessed: October 1, 2020
- Adolescent marijuana use from 2002 to 2008: Higher in states with medical marijuana laws, cause still unclear.Ann Epidemiol. 2011; 21: 714-716
- Association of state recreational marijuana laws with adolescent marijuana Use.JAMA Pediatr. 2017; 171: 142-149
- The availability of medical marijuana dispensary and adolescent marijuana use.Prev Med. 2016; 91: 1-7
- Association of marijuana laws with teen marijuana Use.JAMA Pediatr. 2019; 173: 879-881
- Prevalence of cannabis Use in youths after legalization in Washington state.JAMA Pediatr. 2019; 173: 192-193
- Healthcare Cost and utilization Project (HCUP).Agency for Healthcare Research and Quality, Rockville, MD2019
- Impact of marijuana legalization in Colorado on adolescent emergency and urgent care visits.J Adolesc Health. 2018; 63: 239-241
- Marijuana-related emergency department visits and hospitalizations trend analysis - 2012-2017. Denver Public Health and Denver Department of Public Health and Environment, Denver CO2018
- Common and costly hospitalizations for pediatric mental health disorders.Pediatrics. 2014; 133: 602-609
- Classification System for International classification of Diseases, Ninth Revision, clinical modification and Tenth Revision pediatric mental health disorders.JAMA Pediatr. 2020; 174: 620
- Cannabinoid hyperemesis Syndrome; A Growing concern for New Mexico.ASM. 2018; 2: 1-20
- Acute Illness associated with cannabis Use, by Route of exposure.Ann Intern Med. 2019; 170: 531-537
- Use of census-based aggregate variables to proxy for socioeconomic group: Evidence from national samples.Am J Epidemiol. 1998; 148: 475-486
- Cannabis use disorders are comparatively prevalent among nonwhite racial/ethnic groups and adolescents: A national study.J Psychiatr Res. 2014; 50: 26-35
- Association between recreational marijuana legalization in the United States and changes in marijuana Use and cannabis Use disorder from 2008 to 2016.JAMA Psychiatry. 2020; 77: 165
- Use and abuse of Alcohol and illicit Drugs in US adolescents.Arch Gen Psychiatry. 2012; 69: 390-398
- Psychiatric disorders and trends in Resource Use in pediatric hospitals.Pediatrics. 2016; 138: e20160909
- Acute effects of Smoked and vaporized cannabis in Healthy adults who Infrequently Use cannabis: A Crossover trial.JAMA Netw Open. 2018; 1: e184841
- The impact of marijuana policies on youth: Clinical, research, and legal Update.PEDIATRICS. 2015; 135: e769-e785
- Trends and Correlates of cannabis-involved emergency department visits: 2004 to 2011.J Addict Med. 2016; 10: 429-436
- Marijuana Tourism and emergency department visits in Colorado.The New Engl J Med. 2016; 374: 797-798
Article info
Publication history
Published online: September 09, 2021
Accepted:
July 21,
2021
Received:
March 8,
2021
Footnotes
Financial Disclosure: The authors have no financial disclosures to report.
Conflicts of interest: The authors have no conflicts of interest to report.
Identification
Copyright
© 2021 Society for Adolescent Health and Medicine. All rights reserved.
ScienceDirect
Access this article on ScienceDirectLinked Article
- Contextualizing Cannabis Legalization OutcomesJournal of Adolescent HealthVol. 69Issue 6
- PreviewCannabis (“marijuana”) has a long history of legality and prohibition in the United States. However, it has been federally illegal since the 1970s Controlled Substances Act. The Controlled Substances Act currently categorizes cannabis as a schedule I substance, the most restrictive schedule, quantifying cannabis on par with heroin and indicating a high potential for abuse, no currently accepted medicinal use, and lack of safety for use under medical supervision [1].
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