Journal of Adolescent Health
Volume 41, Issue 1 , Pages 42-50 , July 2007

Interest in Genetic Counseling and Testing for Adolescent Nicotine Addiction Susceptibility among a Sample of Adolescent Medicine Providers Attending a Scientific Conference on Adolescent Health

  • Kenneth P. Tercyak, Ph.D.

      Affiliations

    • Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC
    • Department of Oncology, Georgetown University School of Medicine, Georgetown University Medical Center, Washington, DC
    • Department of Pediatrics, Georgetown University School of Medicine, Georgetown University Medical Center, Washington, DC
    • Corresponding Author InformationAddress correspondence to: Dr. Kenneth P. Tercyak, Cancer Control Program, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, 3300 Whitehaven Street, N.W., Suite 4100, Washington, DC 20007.
  • ,
  • Beth N. Peshkin, M.S., C.G.C.

      Affiliations

    • Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC
    • Department of Oncology, Georgetown University School of Medicine, Georgetown University Medical Center, Washington, DC
  • ,
  • Anisha Abraham, M.D., M.P.H.

      Affiliations

    • Department of Pediatrics, Georgetown University School of Medicine, Georgetown University Medical Center, Washington, DC
  • ,
  • Lauren Wine, B.A.

      Affiliations

    • Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC
  • ,
  • Leslie R. Walker, M.D.

      Affiliations

    • Department of Pediatrics, Georgetown University School of Medicine, Georgetown University Medical Center, Washington, DC

Received 19 September 2006 ,Accepted 28 February 2007.

References 

  1. Schroeder SA. Tobacco still is oral health enemy number one. J Am Dent Assoc. 2006;137:144;146,148
  2. Edwards R. The problem of tobacco smoking. Br Med J. 2004;328:217–219
  3. Vickers KS, Thomas JL, Patten CA, et al. Prevention of tobacco use in adolescents: review of current findings and implications for healthcare providers. Curr Opin Pediatr. 2002;14:708–712
  4. Committee on Substance Abuse. American Academy of Pediatrics: Tobacco’s toll: implications for the pediatrician. Pediatrics. 2001;107:794–798
  5. Kann L, Kinchen SA, Williams BI, et al. Youth risk behavior surveillance—United States, 1997. MMWR CDC Surveill Summ. 1998;47:1–89
  6. Sussman S, Lichtman K, Ritt A, et al. Effects of thirty-four adolescent tobacco use cessation and prevention trials on regular users of tobacco products. Subst Use Misuse. 1999;34:1469–1503
  7. Henningfield JE, Jude NR. Prevention of nicotine addiction: neuropsychopharmacological issues. Nicotine Tob Res. 1999;1(Suppl 1):S41–S48
  8. Wellman RJ, DiFranza JR, Pbert L, et al. A comparison of the psychometric properties of the hooked on nicotine checklist and the modified Fagerstrom tolerance questionnaire. Addict Behav. 2006;31:486–495
  9. DiFranza JR, Savageau JA, Rigotti NA, et al. Development of symptoms of tobacco dependence in youths: 30 month follow up data from the DANDY study. Tob Control. 2002;11:228–235
  10. Lerman C, Berrettini W. Elucidating the role of genetic factors in smoking behavior and nicotine dependence. Am J Med Genet B Neuropsychiatr Genet. 2003;118:48–54
  11. Timberlake DS, Haberstick BC, Lessem JM, et al. An association between the DAT1 polymorphism and smoking behavior in young adults from the national longitudinal study of adolescent health. Health Psychol. 2006;25:190–197
  12. Audrain-McGovern J, Lerman C, Wileyto EP, et al. Interacting effects of genetic predisposition and depression on adolescent smoking progression. Am J Psychiatry. 2004;161:1224–1230
  13. Audrain-McGovern J, Rodriguez D, Wileyto EP, et al. Effect of team sport participation on genetic predisposition to adolescent smoking progression. Arch Gen Psychiatry. 2006;63:433–441
  14. Audrain-McGovern J, Al Koudsi N, Rodriguez D, et al. The role of CYP2A6 in the emergence of nicotine dependence in adolescents. Pediatrics. 2007;119:e264–e274
  15. Harrell JS, Bangdiwala SI, Deng S, et al. Smoking initiation in youth: the roles of gender, race, socioeconomics, and developmental status. J Adolesc Health. 1998;23:271–279
  16. Siqueira L, Diab M, Bodian C, et al. Adolescents becoming smokers: the roles of stress and coping methods. J Adolesc Health. 2000;27:399–408
  17. van den Bree MB, Whitmer MD, Pickworth WB. Predictors of smoking development in a population-based sample of adolescents: a prospective study. J Adolesc Health. 2004;35:172–181
  18. Hall WD. Will nicotine genetics and a nicotine vaccine prevent cigarette smoking and smoking-related diseases?. PLoS Med. 2005;2:e266
  19. Tercyak KP, Peshkin BN, Wine LA, et al. Interest of adolescents in genetic testing for nicotine addiction susceptibility. Prev Med. 2006;42:60–65
  20. Wilfond BS, Geller G, Lerman C, et al. Ethical issues in conducting behavioral genetics research: the case of smoking prevention trials among adolescents. J Health Care Law Policy. 2002;6:73–88
  21. Shields AE, Blumenthal D, Weiss KB, et al. Barriers to translating emerging genetic research on smoking into clinical practice (Perspectives of primary care physicians). J Gen Intern Med. 2005;20:131–138
  22. Acharya K, Ackerman PD, Ross LF. Pediatricians’ attitudes toward expanding newborn screening. Pediatrics. 2005;116:e476–e484
  23. Elster AB, Kuznets NJ. AMA Guidelines for Adolescent Preventive Services (GAPS): Recommendations and Rationale. Baltimore, MD: Williams & Wilkins; 1994;
  24. US Public Health Service. A clinical practice guideline for treating tobacco use and dependence: A US Public Health Service report (The Tobacco Use and Dependence Clinical Practice Guideline Panel, Staff, and Consortium Representatives). JAMA. 2000;283:3244–3254
  25. Kaplan CP, Perez-Stable EJ, Fuentes-Afflick E, et al. Smoking cessation counseling with young patients: the practices of family physicians and pediatricians. Arch Pediatr Adolesc Med. 2004;158:83–90
  26. Shelley D, Cantrell J, Faulkner D, et al. Physician and dentist tobacco use counseling and adolescent smoking behavior: results from the 2000 National Youth Tobacco Survey. Pediatrics. 2005;115:719–725
  27. Thorndike AN, Ferris TG, Stafford RS, et al. Rates of U.S. physicians counseling adolescents about smoking. J Natl Cancer Inst. 1999;91:1857–1862
  28. Lerman C, Patterson F, Berrettini W. Treating tobacco dependence: state of the science and new directions. J Clin Oncol. 2005;23:311–323
  29. Hiatt RA, Rimer BK. A new strategy for cancer control research. Cancer Epidemiol Biomarkers Prev. 1999;8:957–964
  30. Ferguson SL. Every child deserves Bright Futures. J Pediatr Nurs. 1999;14:123–124
  31. Society for Adolescent Medicine. The Older Adolescent/Young Adult. SBM 2005 annual meeting, March 30–April 2, Century City, CA.
  32. Nunnally JC, Bernstein IH. Psychometric Theory. (3rd ed). New York: McGraw-Hill; 1994;
  33. Sieving RE, Beuhring T, Resnick MD, et al. Development of adolescent self-report measures from the National Longitudinal Study of Adolescent Health. J Adolesc Health. 2001;28:73–81
  34. Halpern-Felsher BL, Ozer EM, Millstein SG, et al. Preventive services in a health maintenance organization: how well do pediatricians screen and educate adolescent patients?. Arch Pediatr Adolesc Med. 2000;154:173–179
  35. Anderson LM, May DS. Has the use of cervical, breast, and colorectal cancer screening increased in the United States?. Am J Public Health. 1995;85:840–842
  36. Yarnall KS, Pollak KI, Ostbye T, et al. Primary care: is there enough time for prevention?. Am J Public Health. 2003;93:635–641
  37. Pentel PR, Malin DH, Ennifar S, et al. A nicotine conjugate vaccine reduces nicotine distribution to brain and attenuates its behavioral and cardiovascular effects in rats. Pharmacol Biochem Behav. 2000;65:191–198
  38. Vocci FJ, Chiang CN. Vaccines against nicotine: how effective are they likely to be in preventing smoking?. CNS Drugs. 2001;15:505–514
  39. Hofman KJ, Tambor ES, Chase GA, Geller G, Faden RR, Holtzman NA. Physicians’ knowledge of genetics and genetic tests. Acad Med. 1993;68:625–632
  40. Shields A, Lerman C, Sullivan P. Translating emerging research on the genetics of smoking into clinical practice: ethical and social considerations. Nicotine Tob Res. 2004;6:675–688

PII: S1054-139X(07)00134-6

doi: 10.1016/j.jadohealth.2007.02.017

Journal of Adolescent Health
Volume 41, Issue 1 , Pages 42-50 , July 2007